MT @SeraCare: Highlights from the Precision Medicine World Congress https://t.co/2yOykbsk5O #PMWC17 @PMWCintl https://t.co/rGBJX1JzDM

11:55am March 1st 2017 via Hootsuite

GRAIL repurchases part of Illumina's stake, now at 20% | Seeking Alpha https://t.co/HquJCVTpm9

11:20am March 1st 2017 via Hootsuite

RT @TwoPoreGuys: Thanks for the writeup on our #nanopore tech that was presented at #TRICON @DaleYuzuki. Nice meeting you as well! https://…

11:14am March 1st 2017 via Twitter Web Client

Agonizing Choices for Lives Saved by Miracle Biotech Drugs - WSJ https://t.co/R5sTwRhrP1

10:50am March 1st 2017 via Hootsuite

RT @SeraCare: Join us on Wednesday, March 1 for a live webinar on enabling #clinical #genomics https://t.co/6P5RdViSQx https://t.co/w1ZaKGv…

10:27am March 1st 2017 via Twitter Web Client

Open Science Prize announces epidemic tracking tool as grand prize winner | National Institutes of Health (NIH) https://t.co/FiijxHkVh8

9:38am March 1st 2017 via Hootsuite

New post: A handheld single-molecule diagnostic platform Two Pore Guys https://t.co/MxHgo2bNIi

8:39am March 1st 2017 via WP to TWTR on Yuzuki.org

Patient with a rare disease will get a private meeting with Trump | Stat News https://t.co/dl17rgwU3O

9:51pm February 28th 2017 via Hootsuite

Colorectal cancer rates rising sharply among Gen X and millennials - The Washington Post https://t.co/w1qGTPPBQ0

1:57pm February 28th 2017 via Hootsuite

Enabling Clinical Genomics with Highly Multiplexed and Patient-like Ref Materials Webinar March 1 1PM ET https://t.co/xVpmcE2nhZ @SeraCare

12:35pm February 28th 2017 via Hootsuite

Trisomy Spotted in Chimp | GenomeWeb https://t.co/lXSkX1P3Cs

8:40am February 28th 2017 via Hootsuite

RT @drbachinsky: New program aims to build genetics research capacity in Africa https://t.co/Y2OiSF88QY

8:04am February 28th 2017 via Hootsuite

DIY Gene Editing: Fast, Cheap—and Worrisome - WSJ https://t.co/fIX89SKIDG

7:35pm February 27th 2017 via Hootsuite

When Evidence Says No, but Doctors Say Yes - The Atlantic https://t.co/JqrFHEez1w

5:40pm February 27th 2017 via Hootsuite

A giant neuron found wrapped around entire mouse brain : Nature News https://t.co/rfEkMJNqY0

4:30pm February 27th 2017 via Hootsuite

A CRISPR/Cas9 startup launches on the R&D frontier, working on a one-time fix for Duchenne MD – Endpoints News https://t.co/Dcm1cTrcWu

3:30pm February 27th 2017 via Hootsuite

An epigenetics gold rush: new controls for gene expression : Nature News https://t.co/dNjFF583gE

2:30pm February 27th 2017 via Hootsuite

Going big: Biotech vets blast off with Arrakis on a new journey of RNA exploration – ENDPOINTS NEWS https://t.co/2TWS21bwJw

1:30pm February 27th 2017 via Hootsuite

The genome Aggregation Database (gnomAD) released today | MacArthur Lab https://t.co/TbQ9Pjy0qH

12:25pm February 27th 2017 via Hootsuite

Personalizing Treatment With ctDNA in Prostate Cancer | CURE Magazine https://t.co/Tm3hr5cAdJ

11:25am February 27th 2017 via Hootsuite

Study links working remotely to more stress, insomnia | MedicalXpress https://t.co/HTJzO2wjix

9:25am February 27th 2017 via Hootsuite

RT @biorxivpreprint: Short DNA sequence patterns accurately identify broadlyactive human enhancers https://t.co/GqolOCfKjZ #bioRxiv

9:22am February 27th 2017 via Twitter Web Client

Craig Venter: Trying to decode death | Forbes Video https://t.co/AEGzZdz9jf

8:22am February 27th 2017 via Hootsuite

Biologists propose to sequence the DNA of all life on Earth | Science https://t.co/3XMZWaX5P5

12:50pm February 25th 2017 via Hootsuite

Reddit is Being Manipulated By Big Financial Services Companies | Forbes https://t.co/Vn6UTtwNuz Internet shilling = big business

6:15pm February 24th 2017 via Hootsuite

Paweletz: Truth is clinical outcome: validation PFS by tumor, plasma T790M status, response '16 ref https://t.co/zS75h53t8f #tricon

3:48pm February 24th 2017 via Hootsuite

Paweletz: Truth is clinical outcome: validation of plasma T790M vs response rate. PFS by tumor, plasma T790M status #Tricon

3:46pm February 24th 2017 via Hootsuite

Paweletz: Guardant work (n=113), <0.5% sens for EGFR Ex19del, cp to ddPCR. For L858R, consistent data #Tricon

3:44pm February 24th 2017 via Hootsuite

Paweletz: Blinded analysis of EGFR and KRAS w/matched NGS vs ddCPR results. Sens about 0.5%. '15 ref https://t.co/hiJDLqQeR1 #Tricon

3:42pm February 24th 2017 via Hootsuite

Paweletz: Between ddPCR to BEAMing: 92% concordance; ARMS (cobas) about 85% concordance. 'Not that great' #Tricon

3:40pm February 24th 2017 via Hootsuite

Paweletz: Collab w/Clovis (3rd gen TKI), had to be T790M+ cobas test; did BEAMing, did ddPCR. Truth was tissue. #Tricon

3:39pm February 24th 2017 via Hootsuite

Paweletz: Showed data from prospective clin trial ref https://t.co/mHCqarLRiT and prevalence data #Tricon

3:39pm February 24th 2017 via Hootsuite

Paweletz: Uses contrasting, non-overlapping genotypes, to det gold std pos, neg populations. A ref range for each assay can be ID'd #Tricon

3:37pm February 24th 2017 via Hootsuite

Paweletz: Curves of 60,70,80,90% sens; and 99,95,90% spec - need to move to 100% specificity for clinical util #Tricon

3:36pm February 24th 2017 via Hootsuite

Paweletz: 90% sens, 98% specific, prevalence is 2%. 1K pts, 20 will have mut; 18/20 positive, 2 neg. But of 960 negs, 40 will be FPs #Tricon

3:35pm February 24th 2017 via Hootsuite

Paweletz: Validation of a new plasma assay depends 'on your interpretation of truth'. Discussion of specificity needs revisiting #Tricon

3:34pm February 24th 2017 via Hootsuite

Paweletz: Data for two pts from '14 ref EGFR https://t.co/jX1ubaXSp1 ex19del, EGFR T790M and progression #Tricon

3:32pm February 24th 2017 via Hootsuite

Paweletz: 8/44 no followup; 4/44 insufficient. #Tricon

3:30pm February 24th 2017 via Hootsuite

Paweletz: 3rd-line TKI req ctDNA; Clin trial, n=83 eligable, screen fail n=23; of 60 from '10-'15, 12 ongoing, 44 progressed #Tricon

3:29pm February 24th 2017 via Hootsuite

Paweletz: Lung ca is increasingly a disease of targetable driver genes. Emergence of T790M-mut clones is inevitable #Tricon

3:27pm February 24th 2017 via Twitter Web Client

Paweletz: It is a 'tick-tock' cycle of innovation, biology, assays; lung ca is the 'poster child for personalized med' #Tricon

3:26pm February 24th 2017 via Twitter Web Client

Paweletz: They work with Pharma, CLIA dev, partner with biotech for assay dev/validation/licensing. #Tricon

3:25pm February 24th 2017 via Twitter Web Client

Cloud Paweletz (Dana Farber MA) Monitoring cancer through blood #Tricon

3:24pm February 24th 2017 via Twitter Web Client

Tam: Looking at 0.5% on @archerdx detection (AF from 0.35 to 1.18%) but 5/8 detected at 0.1% (0.1-0.27%) #Tricon

3:16pm February 24th 2017 via Twitter Web Client

Tam: Plans to use @archerdx molecular-tagged cfDNA technology to look at <1% #Tricon

3:12pm February 24th 2017 via Twitter Web Client

Tam: Titrated Acrometrix controls to 1%, was able to show sensitivity for most mutations. Error bkgd ~.5% #Tricon

3:08pm February 24th 2017 via Twitter Web Client

Tam: Needing to go to NGS, used @iontorrent for small input w/AmpliSeq. Complimentary comments about Ion Chef instrument #Tricon

3:07pm February 24th 2017 via Twitter Web Client

Tam: ddPCR cp to qPCR, shows greater sensitivity (not surprisingly) #Tricon

3:03pm February 24th 2017 via Twitter Web Client